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Feasibility, acceptability and use of self-sampling for GeneXpert-based HPV-DNA testing for Cervical Cancer screening in selected rural areas of Bangladesh

Study details

Principal Investigator
Dr Quamrun Nahar
Category
Innovation Studies
Themes
Gender Equity & Rights, Gynecological Issues
Date

Study Overview

HPV DNA testing detects high-risk strains of HPV which cause almost all cervical cancers. Unlike tests that rely on visual inspection, HPV DNA testing is an objective diagnostic test and leaves no space for interpretation of results. WHO recommends HPV DNA for screening and samples can be collected through self-sampling or collected by providers. We will conduct implementation research to assess the feasibility, acceptability, and use of self-sampling for HPV DNA testing to increase coverage of cervical cancer screening in a rural area of Bangladesh. The women who will screen positive will be prospectively followed to assess their compliance related to referral, treatment and further follow-up. The study will be conducted in three purposively selected unions of Faridpur district. The effects of interventions will be assessed by comparing the coverage of women screened for cervical cancer between the two intervention arms and the comparison arm, as well as comparing the compliance related to referral, treatment and further follow-up. We will utilise a mixed-method approach of data collection for the study.

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